clonal anergy

clonal anergy
клональная толерантность

Англо-русский словарь по иммунологии и иммуногенетике. — М.: Русский язык. . 1990.

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  • Clonal anergy — For the use of anergy in thermodynamics, see Exergy. Anergy is a term in immunobiology that describes a lack of reaction by the body s defense mechanisms to foreign substances, and consists of a direct induction of peripheral lymphocyte tolerance …   Wikipedia

  • Clonal — may refer to in Immunology Clonal deletion, a process by which B cells and T cells are deactivated before act significantly upon specific antigens Clonal selection theory, a model for how the immune system responds to infection Clonal anergy, a… …   Wikipedia

  • Clonal deletion — is a process by which B cells and T cells are deactivated after they have expressed receptors for self antigens and before they develop into fully immunocompetent lymphocytes.[1] It is one method of immune tolerance. References ^ Lecture 15… …   Wikipedia

  • clonal deletion theory — a theory of immunologic tolerance to self antigens according to which “forbidden clones” of immunocytes, those reactive with self antigens, are eliminated on contact with antigen during fetal life. The terms “clonal abortion,” “clonal… …   Medical dictionary

  • Molecular mimicry — is defined as the theoretical possibility that sequence similarities between foreign and self peptides are sufficient to result in the cross activation of autoreactive T or B cells by pathogen derived peptides. Despite the promiscuity of several… …   Wikipedia

  • Autoimmunity — Infobox Disease Name = Autoimmunity Caption = DiseasesDB = 28805 ICD10 = ICD9 = ICD9|279.4 ICDO = OMIM = 109100 MedlinePlus = eMedicineSubj = eMedicineTopic = MeshID = D001327 Autoimmunity is the failure of an organism to recognize its own… …   Wikipedia

  • tolerance — 1. The ability to endure or be less responsive to a stimulus, especially over a period of continued exposure. 2. The power of resisting the action of a poison or of taking a drug continuously or in large doses without injurious effects. [L.… …   Medical dictionary

  • Superantigen — [ thumb|Figure 1. Schematic of Superantigen stimulation compared to normal antigen presentation and activation [2] .] Superantigens (SAgs) are secreted proteins (exotoxins) that exhibit highly potent lymphocyte transforming (mitogenic) activity… …   Wikipedia

  • Immune tolerance — or immunological tolerance is the process by which the immune system does not attack an antigen.[1] It can be either natural or self tolerance , in which the body does not mount an immune response to self antigens, or induced tolerance , in which …   Wikipedia

  • Central tolerance — is the mechanism by which newly developing T cells and B cells are rendered non reactive to self[1]. The concept of central tolerance was proposed in 1959 by Joshua Lederberg[2], as part of his general theory of immunity and tolerance, and is… …   Wikipedia

  • Antibody — Immunoglobulin redirects here. For the immunoglobulin family, see Immunoglobulin superfamily. Antibodies redirects here. For the film, see Antibodies (film). Each antibody binds to a specific antigen; an interaction similar to a lock and key. An… …   Wikipedia


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